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Swertia chirata: A medicinal herb and its uses in Unani system of medicine
Mohammed Wasim Ahmed, Mohd Asif, Asma Sattar Khan, Pawan Kumar Sagar, Shoib Ahmed Ansari, Jayanthy A, R. Murugeswaran

Abstract
Swertia chirata Buch.-Ham. ex Wall. is one of the important herb widely explored in the Unani system of medicine. The drug is very potent and efficacious with numerous beneficiary therapeutic actions for treating various human diseases. The plant is originated from Nepal and commonly occurs in the Himalayan region from Kashmir to Arunachal at an altitude of 4 to 10 thousand feet. It has 2 to 4 feet of height and having a prominent bitter taste. The parts of the plants are considered as rich sources of phytochemical ingredients which might play a vital role in disease suppression and extensively exploited in different traditional systems of medicines such as Unani, Ayurveda, and Siddha. Phytochemical analysis of the plants revealed alkaloids, flavonoids, steroids, glycosides, triterpenoids, saponins, xanthones, and ascorbic acid. The main chemical ingredients include Swertiamarin, Amarogentin, Swechirin, Mangiferin, Sweroside, Gentianine, Amaroswerin, Oleanolic acid, Swertanoone, and Ursolic acid. This drug is commonly known as a bitter tonic in traditional system of medicine for the treatment of fever, loss of appetite, digestive disorders, diabetes, jaundice, skin, and various other diseases. The main emphasis in this review has been given on the evidence-based knowledge about Swertia chirata from Unani perspective.

Keywords: Swertia chirata, Unani drug, Disease, Ultra-Dilute, Phytochemical, Bitter.