Ethnopharmacological properties of Capsella bursa-pastoris (L.) Medik and Hedychium
coronarium J.Koenig
Rajendra Gyawali, Tirtha Maiya Shrestha, Nikita Karki, Anjana Khanal, Beenu Shrestha, Manisha Neupane, Samjhana Shrestha
Abstract
Ethnopharmacological evidence confirms the acceptance of botanicals through scientific validation of indigenous practices. Leaves and roots of Capsella bursapastoris (L.) Medik, and Hedychium coronarium J.Koenig are used as vegetable and medicinal purpose in Nepal. Medicinal plants C. bursa-pastoris, and H. coronarium were subjected to phytochemical screening and biological evaluation. Methanolic extract of plant powders were evaluated for their medicinal properties regarding their phytochemical profiles. Anti-microbial anti-inflammatory, antioxidant, wound healing and brine shrimp cytotoxic activities were studied by standard methods. Extracts of the plants showed the activity against Escherichia coli, Staphylococcus aureus and Salmonella typhi. C. bursa-pastoris is found to be active against S. Typhi. Comparatively less toxic and better anti-inflammatory property was exhibited by H. coronarium. The preliminary results are particularly applied among ethnopharmacological practitioners of currently practicing systems of traditional medicine in Nepal. The results will be useful in bioprospecting for clinical application and the development of novel herbal therapeutics or consumer products.
Keywords: Capsella bursa-pastoris (L.) Medik, Hedychium coronarium J.Koenig, Phytochemicals, Ethnopharmacology, Formulation
coronarium J.Koenig
Rajendra Gyawali, Tirtha Maiya Shrestha, Nikita Karki, Anjana Khanal, Beenu Shrestha, Manisha Neupane, Samjhana Shrestha
Abstract
Ethnopharmacological evidence confirms the acceptance of botanicals through scientific validation of indigenous practices. Leaves and roots of Capsella bursapastoris (L.) Medik, and Hedychium coronarium J.Koenig are used as vegetable and medicinal purpose in Nepal. Medicinal plants C. bursa-pastoris, and H. coronarium were subjected to phytochemical screening and biological evaluation. Methanolic extract of plant powders were evaluated for their medicinal properties regarding their phytochemical profiles. Anti-microbial anti-inflammatory, antioxidant, wound healing and brine shrimp cytotoxic activities were studied by standard methods. Extracts of the plants showed the activity against Escherichia coli, Staphylococcus aureus and Salmonella typhi. C. bursa-pastoris is found to be active against S. Typhi. Comparatively less toxic and better anti-inflammatory property was exhibited by H. coronarium. The preliminary results are particularly applied among ethnopharmacological practitioners of currently practicing systems of traditional medicine in Nepal. The results will be useful in bioprospecting for clinical application and the development of novel herbal therapeutics or consumer products.
Keywords: Capsella bursa-pastoris (L.) Medik, Hedychium coronarium J.Koenig, Phytochemicals, Ethnopharmacology, Formulation
