Green synthesis of zinc oxide nanoparticles using leaves extract of Mangifera indica L. and evaluation of its antibacterial activity
Sushma Khatri, Dharma Prasad Khanal
Abstract:
Objectives: The aim of the research study was the synthesis of zinc oxide nanoparticles using leaf extract of Mangifera indica L and the evaluation of its antibacterial activity. Methods: The zinc nanoparticles were synthesized using leaves extract of Mangifera indica L. mixed with zinc acetate. The characterization was done using UV-visible spectroscopy, FTIR, and XRD analysis. Anti-bacterial activity of both the extract and the synthesized nanoparticles was evaluated using the Agar well diffusion method. The characterization of the synthesized zinc nanoparticles was done by using UV-visible spectroscopy which exhibited an optical property as indicated by the surface plasmon resonance at 350nm. FTIR analysis shows the essential functional groups as phenols, carbonyl, alcohol, and alkane. The XRD analysis was used to calculate the size of zinc nanoparticles, and the average size was found to be 11.68nm.
Results: The antibacterial activity of synthesized zinc nanoparticles showed improved sensitivity towards both the gram-positive and gram-negative bacteria in comparison to plain extract. Conclusion: The study shows that zinc nanoparticles possess more promising anti-bacterial activity than plain extract. The synthesis of nanoparticles using the plant source is environment-friendly, cost-effective, and safer.
Keywords: antibacterial activity, Fourier Transform Infrared Spectroscopy (FTIR), Mangifera indica Linn, UV-visible spectroscopy, zinc nanoparticles, X-ray diffraction (XRD)
Sushma Khatri, Dharma Prasad Khanal
Abstract:
Objectives: The aim of the research study was the synthesis of zinc oxide nanoparticles using leaf extract of Mangifera indica L and the evaluation of its antibacterial activity. Methods: The zinc nanoparticles were synthesized using leaves extract of Mangifera indica L. mixed with zinc acetate. The characterization was done using UV-visible spectroscopy, FTIR, and XRD analysis. Anti-bacterial activity of both the extract and the synthesized nanoparticles was evaluated using the Agar well diffusion method. The characterization of the synthesized zinc nanoparticles was done by using UV-visible spectroscopy which exhibited an optical property as indicated by the surface plasmon resonance at 350nm. FTIR analysis shows the essential functional groups as phenols, carbonyl, alcohol, and alkane. The XRD analysis was used to calculate the size of zinc nanoparticles, and the average size was found to be 11.68nm.
Results: The antibacterial activity of synthesized zinc nanoparticles showed improved sensitivity towards both the gram-positive and gram-negative bacteria in comparison to plain extract. Conclusion: The study shows that zinc nanoparticles possess more promising anti-bacterial activity than plain extract. The synthesis of nanoparticles using the plant source is environment-friendly, cost-effective, and safer.
Keywords: antibacterial activity, Fourier Transform Infrared Spectroscopy (FTIR), Mangifera indica Linn, UV-visible spectroscopy, zinc nanoparticles, X-ray diffraction (XRD)
