The effect of Syzygium aromaticum flavonoid-rich fraction on wound healing
Mohd Kamal N.H, Ihsan Safwan K, Daryl Jesus A, Hafidz Hadi A, Zaridah Z, Azman M, Muhammad Haziq Imran J
Abstract:
Context: Recent studies have shown that the aqueous extract of S. aromaticum contains many flavonoids and can still be used for wound healing. Objective: to test S. aromaticum flavonoid fraction on wound healing. Methods: was extracted and analysed for flavonoid content. The fraction was then used in an in vivo wound healing study. In addition, 20 Sprague-Dawley rats weighing 250 to 300 g were used for the in vivo study. Dorsal excisional wounds of approximately 0.8 cm in length were created in each of the five planned groups of rats. The wound area and healing activity were observed every day for up to 10 days. Results: flavonoid fraction heals wounds in rats. Conclusion: flavonoid fraction of S. aromaticum has the potential to be an ingredient for wound healing drugs
Keywords: Syzygium aromaticum; wound healing;
Mohd Kamal N.H, Ihsan Safwan K, Daryl Jesus A, Hafidz Hadi A, Zaridah Z, Azman M, Muhammad Haziq Imran J
Abstract:
Context: Recent studies have shown that the aqueous extract of S. aromaticum contains many flavonoids and can still be used for wound healing. Objective: to test S. aromaticum flavonoid fraction on wound healing. Methods: was extracted and analysed for flavonoid content. The fraction was then used in an in vivo wound healing study. In addition, 20 Sprague-Dawley rats weighing 250 to 300 g were used for the in vivo study. Dorsal excisional wounds of approximately 0.8 cm in length were created in each of the five planned groups of rats. The wound area and healing activity were observed every day for up to 10 days. Results: flavonoid fraction heals wounds in rats. Conclusion: flavonoid fraction of S. aromaticum has the potential to be an ingredient for wound healing drugs
Keywords: Syzygium aromaticum; wound healing;
